• Question: How are these "zebrafish" related to humans?

    Asked by georgewhite98 to Alberto on 18 Jun 2013.
    • Photo: Alberto Lapedriza

      Alberto Lapedriza answered on 18 Jun 2013:


      If you compare a zebrafish with a human you can easily see that we are very different. And you may think that we cannot learn anything from zebrafish to understand and treat human diseases. However, if you look deeper, in the cellular level, you realise we are strikingly similar. The cells from a zebrafish work pretty much in the same way as ours. And recently, we have discovered that more than 70% of the zebrafish genes have a similar one in humans. Therefore, although we look very different, in the molecular and cellular level we work in the same way, and we can learn a lot about how our body works studying zebrafish. That is what makes zebrafish such a great model to study human diseases and possible treatments.

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